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In many chemical processes, the difference between a smooth scale-up and an expensive troubleshooting cycle is not the “big reaction,” but the small intermediate that touches everything downstream. 4 Chlorobutyryl Chloride is often that critical link. It’s selected when your route needs an acyl chloride that can deliver reactivity while keeping structure confirmation straightforward: you can verify it quickly by CAS identity, formula, and physical constants, then move on to the work that matters—yield, selectivity, and impurity control.
On the bench, you notice it immediately: a clean, mobile liquid with a distinct, biting scent that signals “keep it dry and controlled.” In a production setting, that sensory cue is useful—it reminds teams to protect the material from moisture and to run disciplined receiving and storage practices. When those basics are in place, the material becomes a dependable workhorse intermediate: consistent, easy to specify, and practical for process teams who care about reproducibility, audit readiness, and on-time deliveries.
Spec clarity that supports fast incoming QC
Buyers can confirm identity using CAS RN, molecular formula, molecular weight, and key physical constants, reducing time spent on ambiguity during goods receipt.
Process-friendly physical profile
A liquid form simplifies metering and charging in many workflows compared with solids that require dissolution or melting steps.
Moisture-sensitive behavior that encourages good plant discipline
It hydrolyzes in the presence of water, which is a strong reason to keep storage and transfer practices dry—helpful for protecting product quality and lowering waste.
Versatile intermediate for regulated supply chains
Frequently sourced for pharma and agrochemical production planning where documentation, traceability, and lot consistency matter as much as price.
Clear sensory indicators for handling
The liquid’s appearance (clear, colorless to yellowish) and odor (pungent) help operators recognize material condition quickly during routine checks.
For B2B procurement, “good enough” naming is never enough—you need identifiers that match across ERP, COA, SDS, and customs paperwork. This product’s identity is anchored by widely recognized references: CAS RN 4635-59-0, EC/EINECS 225-059-1, and the molecular formula C4H6Cl2O. It is also known under multiple common synonyms used in global trade and technical documentation, including 4-CBC, 4-chlorobutanoyl chloride, and related naming variants. This helps reduce mistakes when different teams, regions, or languages are involved in sourcing.
To make sourcing and regulatory reviews easier, many customers also reference the linear formula representation Cl(CH2)3COCl in internal specs, because it communicates structure quickly during route discussions. If your organization uses internal material codes, we recommend mapping your code to CAS RN and EC number first—this is the simplest way to avoid duplicates and receiving mismatches across sites.
Acyl chlorides are chosen for their reactivity, but that same reactivity demands careful storage discipline. 4 Chlorobutyryl Chloride is moisture sensitive and hydrolyzes in the presence of water. Practically, that means your best outcomes come from controlling humidity exposure, keeping containers tightly closed, and using dry transfer practices appropriate for your site’s safety standards. The material’s pungent odor and clear liquid appearance can help operators quickly recognize leaks or exposure events, which supports safer routine handling.
Best-practice guidance for professional users
Store in a cool, dry, well-ventilated area, away from moisture sources
Keep containers sealed and clearly labeled for batch traceability
Follow your facility’s SOPs and the product SDS for PPE and engineering controls
This section is intentionally operational rather than instructional: your EHS team should set exact procedures based on your plant environment, local regulations, and the SDS.
This intermediate is commonly sourced for pharmaceutical and agrochemical manufacturing, where it functions as a building block used to introduce the 4-chlorobutyryl group into downstream molecules. For B2B customers, the value is less about the reagent itself and more about what it prevents: re-validation delays, extra impurity investigations, and “surprise” variability between lots. When you source a well-specified intermediate with consistent documentation, you reduce downstream uncertainty and shorten your path to stable output.
Where customers typically use it
Route development and optimization for pharma intermediates
Agrochemical intermediate production and process scale-up
Custom synthesis programs requiring repeatable acylation steps
If you are qualifying a new supplier, we recommend evaluating what matters most for your process: impurity limits, moisture control, packaging fit for your equipment, and documentation completeness for your audits.
In regulated and semi-regulated supply chains, documentation is part of the product. A strong supply partner supports your QA workflow with clear communication and stable quality systems. Shandong Jiahong Chemical’s manufacturing background emphasizes process and system management, including long-term development history and multiple management system certifications referenced on the product page. For buyers, this signals a supplier mindset aligned with repeat orders and long-term cooperation rather than one-off spot sales.
What B2B teams usually request
Certificate of Analysis aligned to the agreed specification
SDS for site safety review and transport classification checks
Lot traceability and labeling consistency
Support for sample evaluation and repeat supply planning
If your project requires special documentation formats or internal template alignment, share them early—this helps shorten your supplier qualification timeline.
Chemical procurement is not only chemistry—it’s logistics. Buyers often need packaging that matches storage capacity, charging equipment, and shipping constraints. In the broader market, 4 Chlorobutyryl Chloride is offered in multiple package sizes, from small evaluation packs to industrial packaging and bulk solutions. The right choice depends on how quickly you consume the material, how you transfer liquids, and how you manage moisture exposure.
How to choose packaging
R&D and qualification: smaller packs for controlled evaluation
Pilot and production: packaging sized to minimize container open time
Multi-site supply: standardized labels and pack formats to reduce errors
Tell us your annual volume estimate, preferred incoterms, and destination requirements so we can recommend a packaging approach that is safer, more efficient, and easier to audit.
| Product Name: | 4-Chlorobutyryl chloride |
| Synonyms: | 4-CBC; 4-Chlorobutyrylcy Chloride; 4-chloro butyryl chloride; 4-chlorobutanoyl chloride; 4-CHLOROBUTYL CHLORIDE |
| CAS RN.: | 4635-59-0 |
| EINECS: | 225-059-1 |
| Molecular Weight: | 140.9958 |
| Molecular Formula: | C4H6Cl2O |
| Density: | 1.231g/cm3 |
| Melting Point(℃): | -47℃ |
| Boiling Point(℃): | 174.3°C at 760 mmHg |
| Flash Point(℃): | 70.2°C |
B2B buyers choose suppliers who reduce risk. Our goal is to make 4 Chlorobutyryl Chloride easy to qualify and easy to reorder: clear identifiers, practical physical constants, and a supply approach built for repeat demand. We understand that your real costs are not line items on an invoice—they are the delays caused by inconsistent documentation, unstable lots, and unclear communication when schedules tighten.
What you can expect
Procurement-friendly specification structure that supports internal approvals
Communication aligned with QA and production planning, not just sales
Long-term supply mindset for customers running repeat programs
If you are scaling from lab to pilot or managing multi-site production, we can support a qualification path that fits your timeline and compliance requirements.
Shandong Jiahong Chemical Co., Ltd. was established on June 3, 2002. The company consists of the R&D Department of Shandong Jiahong Chemical Co., Ltd. Shanghai Branch, Shandong Longshengyuan New Material Technology Co., Ltd., and Shandong Zhongda Environmental Technology Co., Ltd. Shandong Jiahong Chemical Industry is one of the top ten industrial backbone enterprises in Gaoqing County, Zibo, a specialized and new small and medium-sized enterprise in Shandong Province, a municipal enterprise technology center, and a municipal green factory. The main products are aluminum-nickel alloy hydrogenation catalysts, fixed bed catalysts, carrier catalysts, copper catalysts, acid chloride series, etc. After more than 20 years of development, with strong technical foundation and quality management experience, we have established more than 10 years of cooperation with hundreds of large enterprises. Through long-term cooperation with the above, and constantly exploring new markets, the company has successively passed ISO9001 quality management system, ISO14001 environmental management system, ISO45001 occupational health management system, intellectual property management system, energy management system, etc. The company has formulated and filed 13 corporate standards, and has a number of R&D patents and utility model patents, which provide effective technical guarantee for the company's product quality. The company participated in the drafting of the industry standard "HG/T 5525-2019 Aluminum Nickel Alloy Hydrogenation Catalyst". While leading the development of the industry, it grasped the future development direction of the industry in advance and won a higher development platform for the future of the company.
Q1 What is the best way to confirm identity during incoming QC
Use the core identifiers and physical constants: CAS RN 4635-59-0, EC 225-059-1, formula C4H6Cl2O, molecular weight 140.9958, and the listed density and boiling point range. Many teams also use appearance checks, since the liquid is typically clear and can be colorless to light yellow.
Q2 Is this product sensitive to water
Yes. It hydrolyzes in the presence of water, so moisture control is important in storage, handling, and transfer. Your EHS team should define exact procedures based on SDS guidance and site conditions.
Q3 What industries typically purchase this material
Common buyers include pharmaceutical manufacturers, agrochemical producers, and custom synthesis teams. It is used as an intermediate where introducing a 4-chlorobutyryl group supports downstream product development and production.
Q4 How do I choose packaging for my operation
Choose packaging that minimizes exposure time after opening and matches your transfer equipment. Smaller packs suit R&D and qualification; larger industrial packs can improve efficiency for steady production. Share your consumption rate and handling setup so packaging can be recommended appropriately.
Q5 What documents can support supplier qualification
B2B customers typically request a COA aligned to the agreed spec and an SDS for safety and transport review. If your company has internal templates or audit requirements, providing them early helps speed up qualification and repeat purchasing.
In many chemical processes, the difference between a smooth scale-up and an expensive troubleshooting cycle is not the “big reaction,” but the small intermediate that touches everything downstream. 4 Chlorobutyryl Chloride is often that critical link. It’s selected when your route needs an acyl chloride that can deliver reactivity while keeping structure confirmation straightforward: you can verify it quickly by CAS identity, formula, and physical constants, then move on to the work that matters—yield, selectivity, and impurity control.
On the bench, you notice it immediately: a clean, mobile liquid with a distinct, biting scent that signals “keep it dry and controlled.” In a production setting, that sensory cue is useful—it reminds teams to protect the material from moisture and to run disciplined receiving and storage practices. When those basics are in place, the material becomes a dependable workhorse intermediate: consistent, easy to specify, and practical for process teams who care about reproducibility, audit readiness, and on-time deliveries.
Spec clarity that supports fast incoming QC
Buyers can confirm identity using CAS RN, molecular formula, molecular weight, and key physical constants, reducing time spent on ambiguity during goods receipt.
Process-friendly physical profile
A liquid form simplifies metering and charging in many workflows compared with solids that require dissolution or melting steps.
Moisture-sensitive behavior that encourages good plant discipline
It hydrolyzes in the presence of water, which is a strong reason to keep storage and transfer practices dry—helpful for protecting product quality and lowering waste.
Versatile intermediate for regulated supply chains
Frequently sourced for pharma and agrochemical production planning where documentation, traceability, and lot consistency matter as much as price.
Clear sensory indicators for handling
The liquid’s appearance (clear, colorless to yellowish) and odor (pungent) help operators recognize material condition quickly during routine checks.
For B2B procurement, “good enough” naming is never enough—you need identifiers that match across ERP, COA, SDS, and customs paperwork. This product’s identity is anchored by widely recognized references: CAS RN 4635-59-0, EC/EINECS 225-059-1, and the molecular formula C4H6Cl2O. It is also known under multiple common synonyms used in global trade and technical documentation, including 4-CBC, 4-chlorobutanoyl chloride, and related naming variants. This helps reduce mistakes when different teams, regions, or languages are involved in sourcing.
To make sourcing and regulatory reviews easier, many customers also reference the linear formula representation Cl(CH2)3COCl in internal specs, because it communicates structure quickly during route discussions. If your organization uses internal material codes, we recommend mapping your code to CAS RN and EC number first—this is the simplest way to avoid duplicates and receiving mismatches across sites.
Acyl chlorides are chosen for their reactivity, but that same reactivity demands careful storage discipline. 4 Chlorobutyryl Chloride is moisture sensitive and hydrolyzes in the presence of water. Practically, that means your best outcomes come from controlling humidity exposure, keeping containers tightly closed, and using dry transfer practices appropriate for your site’s safety standards. The material’s pungent odor and clear liquid appearance can help operators quickly recognize leaks or exposure events, which supports safer routine handling.
Best-practice guidance for professional users
Store in a cool, dry, well-ventilated area, away from moisture sources
Keep containers sealed and clearly labeled for batch traceability
Follow your facility’s SOPs and the product SDS for PPE and engineering controls
This section is intentionally operational rather than instructional: your EHS team should set exact procedures based on your plant environment, local regulations, and the SDS.
This intermediate is commonly sourced for pharmaceutical and agrochemical manufacturing, where it functions as a building block used to introduce the 4-chlorobutyryl group into downstream molecules. For B2B customers, the value is less about the reagent itself and more about what it prevents: re-validation delays, extra impurity investigations, and “surprise” variability between lots. When you source a well-specified intermediate with consistent documentation, you reduce downstream uncertainty and shorten your path to stable output.
Where customers typically use it
Route development and optimization for pharma intermediates
Agrochemical intermediate production and process scale-up
Custom synthesis programs requiring repeatable acylation steps
If you are qualifying a new supplier, we recommend evaluating what matters most for your process: impurity limits, moisture control, packaging fit for your equipment, and documentation completeness for your audits.
In regulated and semi-regulated supply chains, documentation is part of the product. A strong supply partner supports your QA workflow with clear communication and stable quality systems. Shandong Jiahong Chemical’s manufacturing background emphasizes process and system management, including long-term development history and multiple management system certifications referenced on the product page. For buyers, this signals a supplier mindset aligned with repeat orders and long-term cooperation rather than one-off spot sales.
What B2B teams usually request
Certificate of Analysis aligned to the agreed specification
SDS for site safety review and transport classification checks
Lot traceability and labeling consistency
Support for sample evaluation and repeat supply planning
If your project requires special documentation formats or internal template alignment, share them early—this helps shorten your supplier qualification timeline.
Chemical procurement is not only chemistry—it’s logistics. Buyers often need packaging that matches storage capacity, charging equipment, and shipping constraints. In the broader market, 4 Chlorobutyryl Chloride is offered in multiple package sizes, from small evaluation packs to industrial packaging and bulk solutions. The right choice depends on how quickly you consume the material, how you transfer liquids, and how you manage moisture exposure.
How to choose packaging
R&D and qualification: smaller packs for controlled evaluation
Pilot and production: packaging sized to minimize container open time
Multi-site supply: standardized labels and pack formats to reduce errors
Tell us your annual volume estimate, preferred incoterms, and destination requirements so we can recommend a packaging approach that is safer, more efficient, and easier to audit.
| Product Name: | 4-Chlorobutyryl chloride |
| Synonyms: | 4-CBC; 4-Chlorobutyrylcy Chloride; 4-chloro butyryl chloride; 4-chlorobutanoyl chloride; 4-CHLOROBUTYL CHLORIDE |
| CAS RN.: | 4635-59-0 |
| EINECS: | 225-059-1 |
| Molecular Weight: | 140.9958 |
| Molecular Formula: | C4H6Cl2O |
| Density: | 1.231g/cm3 |
| Melting Point(℃): | -47℃ |
| Boiling Point(℃): | 174.3°C at 760 mmHg |
| Flash Point(℃): | 70.2°C |
B2B buyers choose suppliers who reduce risk. Our goal is to make 4 Chlorobutyryl Chloride easy to qualify and easy to reorder: clear identifiers, practical physical constants, and a supply approach built for repeat demand. We understand that your real costs are not line items on an invoice—they are the delays caused by inconsistent documentation, unstable lots, and unclear communication when schedules tighten.
What you can expect
Procurement-friendly specification structure that supports internal approvals
Communication aligned with QA and production planning, not just sales
Long-term supply mindset for customers running repeat programs
If you are scaling from lab to pilot or managing multi-site production, we can support a qualification path that fits your timeline and compliance requirements.
Shandong Jiahong Chemical Co., Ltd. was established on June 3, 2002. The company consists of the R&D Department of Shandong Jiahong Chemical Co., Ltd. Shanghai Branch, Shandong Longshengyuan New Material Technology Co., Ltd., and Shandong Zhongda Environmental Technology Co., Ltd. Shandong Jiahong Chemical Industry is one of the top ten industrial backbone enterprises in Gaoqing County, Zibo, a specialized and new small and medium-sized enterprise in Shandong Province, a municipal enterprise technology center, and a municipal green factory. The main products are aluminum-nickel alloy hydrogenation catalysts, fixed bed catalysts, carrier catalysts, copper catalysts, acid chloride series, etc. After more than 20 years of development, with strong technical foundation and quality management experience, we have established more than 10 years of cooperation with hundreds of large enterprises. Through long-term cooperation with the above, and constantly exploring new markets, the company has successively passed ISO9001 quality management system, ISO14001 environmental management system, ISO45001 occupational health management system, intellectual property management system, energy management system, etc. The company has formulated and filed 13 corporate standards, and has a number of R&D patents and utility model patents, which provide effective technical guarantee for the company's product quality. The company participated in the drafting of the industry standard "HG/T 5525-2019 Aluminum Nickel Alloy Hydrogenation Catalyst". While leading the development of the industry, it grasped the future development direction of the industry in advance and won a higher development platform for the future of the company.
Q1 What is the best way to confirm identity during incoming QC
Use the core identifiers and physical constants: CAS RN 4635-59-0, EC 225-059-1, formula C4H6Cl2O, molecular weight 140.9958, and the listed density and boiling point range. Many teams also use appearance checks, since the liquid is typically clear and can be colorless to light yellow.
Q2 Is this product sensitive to water
Yes. It hydrolyzes in the presence of water, so moisture control is important in storage, handling, and transfer. Your EHS team should define exact procedures based on SDS guidance and site conditions.
Q3 What industries typically purchase this material
Common buyers include pharmaceutical manufacturers, agrochemical producers, and custom synthesis teams. It is used as an intermediate where introducing a 4-chlorobutyryl group supports downstream product development and production.
Q4 How do I choose packaging for my operation
Choose packaging that minimizes exposure time after opening and matches your transfer equipment. Smaller packs suit R&D and qualification; larger industrial packs can improve efficiency for steady production. Share your consumption rate and handling setup so packaging can be recommended appropriately.
Q5 What documents can support supplier qualification
B2B customers typically request a COA aligned to the agreed spec and an SDS for safety and transport review. If your company has internal templates or audit requirements, providing them early helps speed up qualification and repeat purchasing.
